Chemicals and Drugs

Pregnanediol

An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.

Chemical Identity

Chemical Information

Molecular Formula
C21H36O2
Molecular Weight
320.5 g/mol
CAS Registry No.
80-92-2
IUPAC Name
(3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey
YWYQTGBBEZQBGO-BERLURQNSA-N
SMILES
C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C)O
MeSH Unique ID
D011276
Source
PubChem CID 219833

MeSH Record

Classification

Broader headings

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MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WP 530

AMA Style

References

  1. National Library of Medicine. Pregnanediol. Medical Subject Headings (MeSH). 2026. Unique ID D011276. http://id.nlm.nih.gov/mesh/2026/D011276
  2. Pregnanediol. In: Wikipedia. https://en.wikipedia.org/wiki/Pregnanediol
  3. Pregnanediol. In: Wikidata. https://www.wikidata.org/wiki/Q906054
  4. Pregnanediol. In: PubChem Compound. CID 219833. https://pubchem.ncbi.nlm.nih.gov/compound/219833