Structured Summary
Abstract
Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
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Synonyms
17 entry terms
- Antigens, CD41
- CD41 Antigen
- CD41 Antigens
- CD41 Cell Surface Antigen
- GP IIb
- GPalpha IIb
- HUPL-ml Surface Antigen
- Integrin alpha IIb
- Integrin alphaIIb
- Membrane Glycoprotein IIb
- Plasma Membrane Glycoprotein IIb
- Antigen, CD41
- Antigen, HUPL-ml Surface
- Glycoprotein IIb, Membrane
- HUPL ml Surface Antigen
- Surface Antigen, HUPL-ml
- alphaIIb, Integrin
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Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2003; use PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX 1996-2002
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Previous Indexing
- Integrins (1992-1995)
- Platelet Glycoprotein GPIIb-IIIa Complex (1996-2002)
- Platelet Membrane Glycoproteins (1987-2002)
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AMA Style
References
- National Library of Medicine. Platelet Membrane Glycoprotein IIb. Medical Subject Headings (MeSH). 2026. Unique ID D040201. http://id.nlm.nih.gov/mesh/2026/D040201
- Platelet Membrane Glycoprotein IIb. In: Wikipedia. https://en.wikipedia.org/wiki/Integrin_alpha_2b
- Platelet Membrane Glycoprotein IIb. In: Wikidata. https://www.wikidata.org/wiki/Q21107760