Chemicals and Drugs

Placental Lactogen

A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

19 entry terms
  • Choriomammotrophin
  • Choriomammotropin
  • Lactogen Hormone, Placental
  • Mammotropic Hormone, Placental
  • PAPP-D
  • Placental Luteotropin
  • Pregnancy-Associated Plasma Protein D
  • Somatomammotropin, Chorionic
  • Chorionic Somatomammotropin
  • Lactogen, Placental
  • Luteotropin, Placental
  • Placental Mammotropic Hormone
  • Pregnancy Associated Plasma Protein D
  • Chorionic Somatomammotropin, Human
  • HCS (Human Chorionic Somatomammotropin)
  • HPL (Human Placental Lactogen)
  • Human Placental Lactogen
  • Human Chorionic Somatomammotropin
  • Placental Lactogen, Human

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

72(68)

MeSH Record

Previous Indexing

  • Placental Hormones (1966-1967)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.649.692w
  2. D12.644w.548w.726.692w
  3. D12.776w.780.650w

MeSH Record

NLM Classification

WK 920

AMA Style

References

  1. National Library of Medicine. Placental Lactogen. Medical Subject Headings (MeSH). 2026. Unique ID D010928. http://id.nlm.nih.gov/mesh/2026/D010928
  2. Placental Lactogen. In: Wikipedia. https://en.wikipedia.org/wiki/Placental_lactogen
  3. Placental Lactogen. In: Wikidata. https://www.wikidata.org/wiki/Q1960869