Chemicals and Drugs

Pizotyline

Serotonin antagonist used against MIGRAINE DISORDERS and vascular headaches.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Serotonin antagonist used against MIGRAINE DISORDERS and vascular headaches.

Chemical Identity

Chemical Information

Molecular Formula
C19H21NS
Molecular Weight
295.4 g/mol
CAS Registry No.
15574-96-6
IUPAC Name
1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
InChIKey
FIADGNVRKBPQEU-UHFFFAOYSA-N
SMILES
CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
MeSH Unique ID
D010918
Source
PubChem CID 27400

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Pizotifen
  • BC-105
  • Polomigran
  • Sandomigran
  • BC 105
  • BC105

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under THIOPHENES 1975-90

MeSH Record

Previous Indexing

  • Benzocycloheptenes (1973-1974)
  • Piperidines (1972-1974)
  • Thiophenes (1970-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Pizotyline. Medical Subject Headings (MeSH). 2026. Unique ID D010918. http://id.nlm.nih.gov/mesh/2026/D010918
  2. Pizotyline. In: Wikipedia. https://en.wikipedia.org/wiki/Pizotifen
  3. Pizotyline. In: Wikidata. https://www.wikidata.org/wiki/Q413784
  4. Pizotyline. In: PubChem Compound. CID 27400. https://pubchem.ncbi.nlm.nih.gov/compound/27400