Chemicals and Drugs

Pioglitazone

A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.

Chemical Identity

Chemical Information

Molecular Formula
C19H20N2O3S
Molecular Weight
356.4 g/mol
CAS Registry No.
111025-46-8
IUPAC Name
5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
InChIKey
HYAFETHFCAUJAY-UHFFFAOYSA-N
SMILES
CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
MeSH Unique ID
D000077205
Source
PubChem CID 4829

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

10 entry terms
  • 5-(4-(2-(5-Ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
  • AD 4833
  • AD-4833
  • Actos
  • Pioglitazone Hydrochloride
  • U 72107A
  • U-72107A
  • U72,107A
  • AD4833
  • U72107A

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1989)

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.675.933w.250w
  2. D03w.383.129w.708.933w.250w

AMA Style

References

  1. National Library of Medicine. Pioglitazone. Medical Subject Headings (MeSH). 2026. Unique ID D000077205. http://id.nlm.nih.gov/mesh/2026/D000077205
  2. Pioglitazone. In: Wikipedia. https://en.wikipedia.org/wiki/Pioglitazone
  3. Pioglitazone. In: Wikidata. https://www.wikidata.org/wiki/Q417765
  4. Pioglitazone. In: PubChem Compound. CID 4829. https://pubchem.ncbi.nlm.nih.gov/compound/4829