Diseases

Pheochromocytoma

A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

MeSH Record

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MeSH Record

See Also

MeSH Record

Synonyms

6 entry terms
  • Pheochromocytomas
  • Pheochromocytoma, Extra-Adrenal
  • Extra-Adrenal Pheochromocytoma
  • Extra-Adrenal Pheochromocytomas
  • Pheochromocytoma, Extra Adrenal
  • Pheochromocytomas, Extra-Adrenal

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

benign or malignant; coord IM with usually ADRENAL GLAND NEOPLASMS (IM)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.465.625w.650w.700w.725w
  2. C04w.557.580.625w.650w.700w.725w

AMA Style

References

  1. National Library of Medicine. Pheochromocytoma. Medical Subject Headings (MeSH). 2026. Unique ID D010673. http://id.nlm.nih.gov/mesh/2026/D010673
  2. Pheochromocytoma. In: Wikipedia. https://en.wikipedia.org/wiki/Pheochromocytoma
  3. Pheochromocytoma. In: Wikidata. https://www.wikidata.org/wiki/Q536269