Chemicals and Drugs

Phenylbutazone

A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.

Chemical Identity

Chemical Information

Molecular Formula
C19H20N2O2
Molecular Weight
308.4 g/mol
CAS Registry No.
50-33-9
IUPAC Name
4-butyl-1,2-diphenylpyrazolidine-3,5-dione
InChIKey
VYMDGNCVAMGZFE-UHFFFAOYSA-N
SMILES
CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
MeSH Unique ID
D010653
Source
PubChem CID 4781

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Diphenylbutazone
  • Butacote
  • Butadion
  • Butadione
  • Butapirazol
  • Butapyrazole
  • Butazolidin
  • Fenilbutazon

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 95

AMA Style

References

  1. National Library of Medicine. Phenylbutazone. Medical Subject Headings (MeSH). 2026. Unique ID D010653. http://id.nlm.nih.gov/mesh/2026/D010653
  2. Phenylbutazone. In: Wikipedia. https://en.wikipedia.org/wiki/Phenylbutazone
  3. Phenylbutazone. In: Wikidata. https://www.wikidata.org/wiki/Q421342
  4. Phenylbutazone. In: PubChem Compound. CID 4781. https://pubchem.ncbi.nlm.nih.gov/compound/4781