Diseases

Peutz-Jeghers Syndrome

A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.

MeSH Record

Classification

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MeSH Record

Synonyms

28 entry terms
  • Lentiginosis, Perioral
  • Periorificial Lentiginosis Syndrome
  • Peutz-Jegher's Syndrome
  • Peutz-Jeghers Polyposis
  • Polyposis, Hamartomatous Intestinal
  • Polyps-and-Spots Syndrome
  • Hamartomatous Intestinal Polyposes
  • Hamartomatous Intestinal Polyposis
  • Intestinal Polyposes, Hamartomatous
  • Intestinal Polyposis, Hamartomatous
  • Lentiginoses, Perioral
  • Perioral Lentiginoses
  • Perioral Lentiginosis
  • Periorificial Lentiginosis Syndromes
  • Peutz Jegher's Syndrome
  • Peutz Jeghers Polyposis
  • Peutz Jeghers Syndrome
  • Peutz-Jegher Syndrome
  • Polyposes, Hamartomatous Intestinal
  • Polyposis, Peutz-Jeghers
  • Polyps and Spots Syndrome
  • Polyps-and-Spots Syndromes
  • Syndrome, Periorificial Lentiginosis
  • Syndrome, Peutz-Jegher's
  • Syndrome, Peutz-Jeghers
  • Syndrome, Polyps-and-Spots
  • Syndromes, Periorificial Lentiginosis
  • Syndromes, Polyps-and-Spots

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

65; was see under POLYPI (now POLYPS) 1963-64

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Peutz-Jeghers Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D010580. http://id.nlm.nih.gov/mesh/2026/D010580
  2. Peutz-Jeghers Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Peutz%E2%80%93Jeghers_syndrome
  3. Peutz-Jeghers Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1544989