Chemicals and Drugs

Peroxisomal Biogenesis Factor 2

A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A multi-pass transmembrane protein that contains a C-terminal RING finger domain. It localizes to the PEROXISOME membrane and is essential for peroxisome biogenesis. Mutations in the PEX2 gene are associated with ZELLWEGER SYNDROME and INFANTILE REFSUM DISEASE.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • PMP35
  • Peroxin-2
  • Peroxisomal Membrane Protein 35
  • Peroxisome Assembly Factor-1
  • Peroxisome Biogenesis Factor 2
  • Peroxin 2
  • Peroxisome Assembly Factor 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1991)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.635w.500
  2. D12.776w.543w.689

AMA Style

References

  1. National Library of Medicine. Peroxisomal Biogenesis Factor 2. Medical Subject Headings (MeSH). 2026. Unique ID D000074428. http://id.nlm.nih.gov/mesh/2026/D000074428
  2. Peroxisomal Biogenesis Factor 2. In: Wikidata. https://www.wikidata.org/wiki/Q21122491