Chemicals and Drugs

Pancuronium

A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.

Chemical Identity

Chemical Information

Molecular Formula
C35H60N2O4+2
Molecular Weight
572.9 g/mol
CAS Registry No.
16974-53-1
IUPAC Name
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
InChIKey
GVEAYVLWDAFXET-XGHATYIMSA-N
SMILES
CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1[N+]4(CCCCC4)C)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C
MeSH Unique ID
D010197
Source
PubChem CID 441289

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Pancuronium Bromide
  • Pancuronium Curamed
  • Pancuronium Organon
  • Pavulon
  • Bromide, Pancuronium

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(72)

MeSH Record

Previous Indexing

  • Androstanes (1968-1971)
  • Curare-Like Agents (1970-1971)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.054.040w.685

AMA Style

References

  1. National Library of Medicine. Pancuronium. Medical Subject Headings (MeSH). 2026. Unique ID D010197. http://id.nlm.nih.gov/mesh/2026/D010197
  2. Pancuronium. In: Wikidata. https://www.wikidata.org/wiki/Q424297
  3. Pancuronium. In: PubChem Compound. CID 441289. https://pubchem.ncbi.nlm.nih.gov/compound/441289