Diseases

Palmoplantar Epidermolytic Keratoderma

An autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. It has been associated with mutations in the gene that codes for KERATIN-9.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. It has been associated with mutations in the gene that codes for KERATIN-9.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

24 entry terms
  • EPPK (Epidermolytic Palmoplantar Keratoderma)
  • Hyperkeratosis, Localized Epidermolytic
  • Keratoderma, Epidermolytic Palmoplantar
  • Keratoderma, Palmoplantar, Epidermolytic
  • Palmoplantar Keratoderma, Epidermolytic
  • Thost-Unna Disease, Epidermolytic
  • Unna-Thost Disease, Epidermolytic
  • EPPKs (Epidermolytic Palmoplantar Keratoderma)
  • Epidermolytic Hyperkeratoses, Localized
  • Epidermolytic Hyperkeratosis, Localized
  • Epidermolytic Palmoplantar Keratoderma
  • Epidermolytic Palmoplantar Keratodermas
  • Epidermolytic Thost-Unna Disease
  • Epidermolytic Unna-Thost Disease
  • Hyperkeratoses, Localized Epidermolytic
  • Keratodermas, Epidermolytic Palmoplantar
  • Localized Epidermolytic Hyperkeratoses
  • Localized Epidermolytic Hyperkeratosis
  • Palmoplantar Keratodermas, Epidermolytic
  • Thost Unna Disease, Epidermolytic
  • Unna Thost Disease, Epidermolytic
  • Epidermolytic Palmoplantar Keratoderma Vorner Type
  • Keratosis of Greither
  • Greither Keratosis

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2007

MeSH Record

Previous Indexing

  • Keratoderma, Palmoplantar, Diffuse (1989-2006)

MeSH Hierarchy

Tree Numbers

  1. C16w.320w.850w.475w.440.500w
  2. C17.800w.428w.435w.440.500w
  3. C17.800w.827w.475w.440.500w

AMA Style

References

  1. National Library of Medicine. Palmoplantar Epidermolytic Keratoderma. Medical Subject Headings (MeSH). 2026. Unique ID D053546. http://id.nlm.nih.gov/mesh/2026/D053546
  2. Palmoplantar Epidermolytic Keratoderma. In: Wikipedia. https://en.wikipedia.org/wiki/Diffuse_epidermolytic_palmoplantar_keratoderma
  3. Palmoplantar Epidermolytic Keratoderma. In: Wikidata. https://www.wikidata.org/wiki/Q5275412