Structured Summary
Abstract
An autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (KERATODERMA, PALMOPLANTAR), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.
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Classification
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Synonyms
9 entry terms
- Keratoderma, Palmoplantar, Diffuse
- Thost-Unna Syndrome
- Tylosis
- Unna-Thost Syndrome
- Syndrome, Thost-Unna
- Syndrome, Unna-Thost
- Thost Unna Syndrome
- Unna Thost Syndrome
- Keratosis Palmaris et Plantaris Familiaris
MeSH Record
Aspects Covered
35 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
Indexing Annotation
do not confuse with KERATODERMA, PALMOPLANTAR
MeSH Record
History Note
90
MeSH Record
Previous Indexing
- Keratoderma, Palmoplantar (1974-1989)
- Keratosis (1966-1973)
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AMA Style
References
- National Library of Medicine. Palmoplantar Diffuse Keratoderma. Medical Subject Headings (MeSH). 2026. Unique ID D015776. http://id.nlm.nih.gov/mesh/2026/D015776
- Palmoplantar Diffuse Keratoderma. In: Wikidata. https://www.wikidata.org/wiki/Q5275419