Chemicals and Drugs

Norepinephrine

Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic.

Chemical Identity

Chemical Information

Molecular Formula
C8H11NO3
Molecular Weight
169.18 g/mol
CAS Registry No.
51-41-2
IUPAC Name
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
InChIKey
SFLSHLFXELFNJZ-QMMMGPOBSA-N
SMILES
C1=CC(=C(C=C1[C@H](CN)O)O)O
MeSH Unique ID
D009638
Source
PubChem CID 439260

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

23 entry terms
  • Levarterenol
  • Levonorepinephrine
  • Noradrenaline
  • Arterenol
  • Levonor
  • Levophed
  • Levophed Bitartrate
  • Noradrenaline Bitartrate
  • Noradrénaline tartrate renaudin
  • Norepinephrin d-Tartrate (1:1)
  • Norepinephrine Bitartrate
  • Norepinephrine Hydrochloride
  • Norepinephrine Hydrochloride, (+)-Isomer
  • Norepinephrine Hydrochloride, (+,-)-Isomer
  • Norepinephrine d-Tartrate (1:1)
  • Norepinephrine l-Tartrate (1:1)
  • Norepinephrine l-Tartrate (1:1), (+,-)-Isomer
  • Norepinephrine l-Tartrate (1:1), Monohydrate
  • Norepinephrine l-Tartrate (1:1), Monohydrate, (+)-Isomer
  • Norepinephrine l-Tartrate (1:2)
  • Norepinephrine l-Tartrate, (+)-Isomer
  • Norepinephrine, (+)-Isomer
  • Norepinephrine, (+,-)-Isomer

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1993 (1963); use ARTERENOL 1974-1993; use LEVONOREPINEPHRINE 1963-1965

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.291.502w
  2. D02w.092w.063w.480w
  3. D02w.092w.211w.215.746w
  4. D02w.092w.311w.830w
  5. D02w.455w.426w.559w.389.657w.166.175w.830w

MeSH Record

NLM Classification

WK 725

AMA Style

References

  1. National Library of Medicine. Norepinephrine. Medical Subject Headings (MeSH). 2026. Unique ID D009638. http://id.nlm.nih.gov/mesh/2026/D009638
  2. Norepinephrine. In: Wikipedia. https://en.wikipedia.org/wiki/Norepinephrine
  3. Norepinephrine. In: Wikidata. https://www.wikidata.org/wiki/Q186242
  4. Norepinephrine. In: PubChem Compound. CID 439260. https://pubchem.ncbi.nlm.nih.gov/compound/439260