Chemicals and Drugs

Nordefrin

A norepinephrine derivative used as a vasoconstrictor agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A norepinephrine derivative used as a vasoconstrictor agent.

Chemical Identity

Chemical Information

Molecular Formula
C9H13NO3
Molecular Weight
183.20 g/mol
CAS Registry No.
829-74-3
IUPAC Name
4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
InChIKey
GEFQWZLICWMTKF-CDUCUWFYSA-N
SMILES
C[C@@H]([C@@H](C1=CC(=C(C=C1)O)O)O)N
MeSH Unique ID
D008771
Source
PubChem CID 164739

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

29 entry terms
  • 3,4-Dihydroxynorephedrine
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol
  • Norephrine
  • alpha-Methylnoradrenaline
  • alpha-Methylnorepinephrine
  • 3,4 Dihydroxynorephedrine
  • alpha Methylnoradrenaline
  • alpha Methylnorepinephrine
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,R*)-(+,-)-Isomer
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,S*)-(+-)-Isomer
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,R*), (R*,R*)-Isomer
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,S*), (R*,R*)-Isomer
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,R*)-Isomer
  • 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,S*)-Isomer
  • Cobefrine
  • Corbadrine
  • Levonordefrin
  • Methylnorepinephrine
  • Neo-Cobefrin
  • Nordefrin Hydrochloride
  • Nordefrin Hydrochloride, (R*,R*)-(+,-)-Isomer
  • Nordefrin Hydrochloride, (R*,S*)-(+,-)-Isomer
  • Nordefrin Tartrate, (R*,R*), (R*,R*) Isomer
  • Nordefrin Tartrate, (R*,S*), (R*,R*) Isomer
  • Nordefrin, (R*,R*)-Isomer
  • Nordefrin, (R*,S*)-Isomer
  • Hydrochloride, Nordefrin
  • Neo Cobefrin
  • NeoCobefrin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was METHYLNOREPINEPHRINE see under NOREPINEPHRINE/analogs & derivatives 1975-90, see under NORMETANEPHRINE 1971-74, & see NORMETANEPHRINE 1966-70

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Nordefrin. Medical Subject Headings (MeSH). 2026. Unique ID D008771. http://id.nlm.nih.gov/mesh/2026/D008771
  2. Nordefrin. In: Wikipedia. https://en.wikipedia.org/wiki/Corbadrine
  3. Nordefrin. In: Wikidata. https://www.wikidata.org/wiki/Q12745763
  4. Nordefrin. In: PubChem Compound. CID 164739. https://pubchem.ncbi.nlm.nih.gov/compound/164739