Chemicals and Drugs

Nogo Receptors

GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini that are connected to the GPI by a stalk region rich in prolines, serines and threonines. They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED GLYCOPROTEIN and other cell surface glycoproteins. Interactions between Nogo receptors and their ligands modulate nerve growth and NEURONAL PLASTICITY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini that are connected to the GPI by a stalk region rich in prolines, serines and threonines. They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED GLYCOPROTEIN and other cell surface glycoproteins. Interactions between Nogo receptors and their ligands modulate nerve growth and NEURONAL PLASTICITY.

MeSH Record

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MeSH Record

Synonyms

3 entry terms
  • Nogo Receptor
  • Receptor, Nogo
  • Receptors, Nogo

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • GPI-Linked Proteins (2010-2016)
  • Myelin Proteins (2001-2016)
  • Receptors, Cell Surface (2001-2016)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.448.738
  2. D12.776w.395w.550w.448.738
  3. D12.776w.543w.484w.500.738
  4. D12.776w.543w.550w.418.738
  5. D12.776w.543w.750w.600
  6. D12.776w.631w.651

AMA Style

References

  1. National Library of Medicine. Nogo Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D000070156. http://id.nlm.nih.gov/mesh/2026/D000070156
  2. Nogo Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q76740790