Chemicals and Drugs

Nogo Receptor 1

A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN. It is expressed primarily by neurons in the brain and OLFACTORY BULBS. During embryonic development, it is expressed in the PERIPHERAL NERVOUS SYSTEM. It localizes to GROWTH CONES and may inhibit neurite outgrowth following SPINAL INJURY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN. It is expressed primarily by neurons in the brain and OLFACTORY BULBS. During embryonic development, it is expressed in the PERIPHERAL NERVOUS SYSTEM. It localizes to GROWTH CONES and may inhibit neurite outgrowth following SPINAL INJURY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

10 entry terms
  • NgR1 Protein
  • Nogo-66 Receptor
  • RTN4R Protein
  • Reticulon-4 Receptor
  • Nogo 66 Receptor
  • Protein, NgR1
  • Protein, RTN4R
  • Receptor, Nogo-66
  • Receptor, Reticulon-4
  • Reticulon 4 Receptor

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • GPI-Linked Proteins (2004-2016)
  • Myelin Proteins (2004-2016)
  • Receptors, Cell Surface (2004-2016)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.448.738.500
  2. D12.776w.395w.550w.448.738.500
  3. D12.776w.543w.484w.500.738.500
  4. D12.776w.543w.550w.418.738.500
  5. D12.776w.543w.750w.600.500
  6. D12.776w.631w.651.500

AMA Style

References

  1. National Library of Medicine. Nogo Receptor 1. Medical Subject Headings (MeSH). 2026. Unique ID D000070816. http://id.nlm.nih.gov/mesh/2026/D000070816
  2. Nogo Receptor 1. In: Wikidata. https://www.wikidata.org/wiki/Q21118558