Chemicals and Drugs

Niacinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Chemical Identity

Chemical Information

Molecular Formula
C6H6N2O
Molecular Weight
122.12 g/mol
CAS Registry No.
98-92-0
IUPAC Name
pyridine-3-carboxamide
InChIKey
DFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILES
C1=CC(=CN=C1)C(=O)N
MeSH Unique ID
D009536
Source
PubChem CID 936

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • 3-Pyridinecarboxamide
  • Nicotinamide
  • Vitamin B 3
  • Vitamin B3
  • Vitamin PP
  • 3 Pyridinecarboxamide
  • B 3, Vitamin
  • B3, Vitamin
  • Enduramide
  • Nicobion
  • Nicotinsäureamid Jenapharm
  • Papulex
  • Jenapharm, Nicotinsäureamid

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/defic: consider also PELLAGRA; /ther use: coordinate disease with /drug ther, not /diet ther

MeSH Record

History Note

93; was NICOTINAMIDE 1963-92; NIACINAMIDE was see NICOTINAMIDE 1963-92

MeSH Hierarchy

Tree Numbers

  1. D03w.066.515w.530w
  2. D03w.383.725w.547w.530w

AMA Style

References

  1. National Library of Medicine. Niacinamide. Medical Subject Headings (MeSH). 2026. Unique ID D009536. http://id.nlm.nih.gov/mesh/2026/D009536
  2. Niacinamide. In: Wikipedia. https://en.wikipedia.org/wiki/Nicotinamide
  3. Niacinamide. In: Wikidata. https://www.wikidata.org/wiki/Q192423
  4. Niacinamide. In: PubChem Compound. CID 936. https://pubchem.ncbi.nlm.nih.gov/compound/936