Structured Summary
Abstract
Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
4 entry terms
- NRP2 Protein
- Npn-2 Protein
- Neuropilin 2
- Npn 2 Protein
MeSH Record
Aspects Covered
19 allowable subheadings
Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2003; for NPN-2 PROTEIN use NEUROPILIN-1 1998-2002
MeSH Record
Previous Indexing
- Nerve Tissue Proteins (1998-2002)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Neuropilin-2. Medical Subject Headings (MeSH). 2026. Unique ID D039943. http://id.nlm.nih.gov/mesh/2026/D039943
- Neuropilin-2. In: Wikidata. https://www.wikidata.org/wiki/Q24725631