Structured Summary
Abstract
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
1 entry terms
- Neurofibromas
MeSH Record
Aspects Covered
38 allowable subheadings
Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, ultrastructure, urine, veterinary, virology.
MeSH Record
Indexing Annotation
solitary; multiple = NEUROFIBROMATOSES but see MeSH definition; coord IM with precoord organ/neopl term (IM)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Neurofibroma. Medical Subject Headings (MeSH). 2026. Unique ID D009455. http://id.nlm.nih.gov/mesh/2026/D009455
- Neurofibroma. In: Wikipedia. https://en.wikipedia.org/wiki/Neurofibroma
- Neurofibroma. In: Wikidata. https://www.wikidata.org/wiki/Q1418735