Chemicals and Drugs

N,N-Dimethyltryptamine

An N-methylated indoleamine derivative and serotonergic hallucinogen which occurs naturally and ubiquitously in several plant species including Psychotria veridis. It also occurs in trace amounts in mammalian brain, blood, and urine, and is known to act as an agonist or antagonist of certain SEROTONIN RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An N-methylated indoleamine derivative and serotonergic hallucinogen which occurs naturally and ubiquitously in several plant species including Psychotria veridis. It also occurs in trace amounts in mammalian brain, blood, and urine, and is known to act as an agonist or antagonist of certain SEROTONIN RECEPTORS.

Chemical Identity

Chemical Information

Molecular Formula
C12H16N2
Molecular Weight
188.27 g/mol
CAS Registry No.
61-50-7
IUPAC Name
2-(1H-indol-3-yl)-N,N-dimethylethanamine
InChIKey
DMULVCHRPCFFGV-UHFFFAOYSA-N
SMILES
CN(C)CCC1=CNC2=CC=CC=C21
MeSH Unique ID
D004130
Source
PubChem CID 6089

MeSH Record

Classification

Broader headings

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Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Dimethyltryptamine
  • N,N Dimethyltryptamine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(89); was see under TRYPTAMINES 1989-90; was DIMETHYLTRYPTAMINE 1973-88 (Prov 1973-74)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.211w.215.801w.451w
  2. D03w.633.100.473.914w.237w

AMA Style

References

  1. National Library of Medicine. N,N-Dimethyltryptamine. Medical Subject Headings (MeSH). 2026. Unique ID D004130. http://id.nlm.nih.gov/mesh/2026/D004130
  2. N,N-Dimethyltryptamine. In: Wikipedia. https://en.wikipedia.org/wiki/Dimethyltryptamine
  3. N,N-Dimethyltryptamine. In: Wikidata. https://www.wikidata.org/wiki/Q407217
  4. N,N-Dimethyltryptamine. In: PubChem Compound. CID 6089. https://pubchem.ncbi.nlm.nih.gov/compound/6089