Chemicals and Drugs

Methoxydimethyltryptamines

Compounds that contain the biogenic monoamine tryptamine and are substituted with one methoxy group and two methyl groups. Members of this group include several potent serotonergic hallucinogens found in several unrelated plants, skins of certain toads, and in mammalian brains. They are possibly involved in the etiology of schizophrenia.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Compounds that contain the biogenic monoamine tryptamine and are substituted with one methoxy group and two methyl groups. Members of this group include several potent serotonergic hallucinogens found in several unrelated plants, skins of certain toads, and in mammalian brains. They are possibly involved in the etiology of schizophrenia.

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Classification

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MeSH Record

Synonyms

6 entry terms
  • 5-Methoxy-N,N-Dimethyltryptamine
  • Methoxydimethyltryptamine
  • Methylbufotenin
  • N,N-Dimethyl-5-Methoxytryptamine
  • 5 Methoxy N,N Dimethyltryptamine
  • N,N Dimethyl 5 Methoxytryptamine

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn /physiol permitted

MeSH Record

History Note

91(84); was see under TRYPTAMINES 1989-90; was see under SEROTONIN 1984-88; was METHOXYDIMETHYLTRYPTAMINE see under SEROTONIN 1980-83

MeSH Record

Previous Indexing

  • Bufotenin (1966-1974) /analogs & derivatives (1975-1979)
  • Dimethyltryptamine (1973-1979)
  • Serotonin (1966-1974) /analogs & derivatives (1975-1979)
  • Tryptamines (1966-1973)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Methoxydimethyltryptamines. Medical Subject Headings (MeSH). 2026. Unique ID D008732. http://id.nlm.nih.gov/mesh/2026/D008732
  2. Methoxydimethyltryptamines. In: Wikidata. https://www.wikidata.org/wiki/Q76850646