Structured Summary
Abstract
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of SKELETAL MYOCYTES. Defects in the SCN4A gene, which codes for the alpha subunit of this sodium channel, are associated with several MYOTONIC DISORDERS.
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Synonyms
12 entry terms
- Type 4 Voltage-Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 4
- NAV1.4 Voltage Gated Sodium Channel
- Type 4 Voltage Gated Sodium Channel
- Voltage Gated Sodium Channel Type 4
- NAV1.4 alpha Subunit
- SCN4A Sodium Channel alpha Subunit
- Sodium Channel, Voltage-Gated, Type IV, alpha 1 Subunit
- Voltage-Gated Sodium Channel Type 4 Subunit alpha
- Subunit, NAV1.4 alpha
- Voltage Gated Sodium Channel Type 4 Subunit alpha
- alpha Subunit, NAV1.4
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2013
MeSH Record
Previous Indexing
- Sodium Channels (1989-2012)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. NAV1.4 Voltage-Gated Sodium Channel. Medical Subject Headings (MeSH). 2026. Unique ID D062553. http://id.nlm.nih.gov/mesh/2026/D062553
- NAV1.4 Voltage-Gated Sodium Channel. In: Wikidata. https://www.wikidata.org/wiki/Q24787143