Anatomy

Mononuclear Phagocyte System

Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Mononuclear cells with pronounced phagocytic ability that are distributed extensively in lymphoid and other organs. It includes MACROPHAGES and their precursors; PHAGOCYTES; KUPFFER CELLS; HISTIOCYTES; DENDRITIC CELLS; LANGERHANS CELLS; and MICROGLIA. The term mononuclear phagocyte system has replaced the former reticuloendothelial system, which also included less active phagocytic cells such as fibroblasts and endothelial cells. (From Illustrated Dictionary of Immunology, 2d ed.)

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Synonyms

4 entry terms
  • Reticuloendothelial System
  • Phagocyte System, Mononuclear
  • System, Mononuclear Phagocyte
  • System, Reticuloendothelial

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings abnormalities, anatomy & histology, blood supply, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, innervation, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, ultrastructure, virology.

MeSH Hierarchy

Tree Number

  1. A15.382w.670

MeSH Record

NLM Classification

WH 650

AMA Style

References

  1. National Library of Medicine. Mononuclear Phagocyte System. Medical Subject Headings (MeSH). 2026. Unique ID D012157. http://id.nlm.nih.gov/mesh/2026/D012157
  2. Mononuclear Phagocyte System. In: Wikidata. https://www.wikidata.org/wiki/Q929966