Chemicals and Drugs

Mitogen-Activated Protein Kinase Kinase Kinase 11

A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Mixed Lineage Kinase 3
  • Mixed Lineage Kinase-3

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2024 (1997)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.559w.650
  2. D12.776w.476.563w.554w.650

AMA Style

References

  1. National Library of Medicine. Mitogen-Activated Protein Kinase Kinase Kinase 11. Medical Subject Headings (MeSH). 2026. Unique ID D000097767. http://id.nlm.nih.gov/mesh/2026/D000097767
  2. Mitogen-Activated Protein Kinase Kinase Kinase 11. In: Wikidata. https://www.wikidata.org/wiki/Q21171701