Chemicals and Drugs

Member 7 Tumor Necrosis Factor Receptor Superfamily

A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation of the receptor by CD70 ANTIGEN results in the increased proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation of the receptor by CD70 ANTIGEN results in the increased proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • Antigen, CD27
  • Antigens, CD27
  • CD27 Antigens
  • T-Cell Activation Antigen
  • TNFRSF7 Receptor
  • Tumor Necrosis Factor Receptor Superfamily, Member 7
  • Activation Antigen, T-Cell
  • Antigen, T-Cell Activation
  • CD27 Antigen
  • Receptor, TNFRSF7
  • T Cell Activation Antigen

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1989); use CD27 ANTIGEN 1989-1993

MeSH Record

Previous Indexing

  • Antigens, CD (1989-1993)
  • Antigens, Differentiation, T-Lymphocyte (1989-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.705w.852w.760w.048w
  2. D23.050w.301.264.894.127w
  3. D23.101w.100.894.127w

AMA Style

References

  1. National Library of Medicine. Member 7 Tumor Necrosis Factor Receptor Superfamily. Medical Subject Headings (MeSH). 2026. Unique ID D018127. http://id.nlm.nih.gov/mesh/2026/D018127
  2. Member 7 Tumor Necrosis Factor Receptor Superfamily. In: Wikipedia. https://en.wikipedia.org/wiki/CD27
  3. Member 7 Tumor Necrosis Factor Receptor Superfamily. In: Wikidata. https://www.wikidata.org/wiki/Q2805224