Chemicals and Drugs

Memantine

AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.

Chemical Identity

Chemical Information

Molecular Formula
C12H21N
Molecular Weight
179.30 g/mol
CAS Registry No.
19982-08-2
IUPAC Name
3,5-dimethyladamantan-1-amine
InChIKey
BUGYDGFZZOZRHP-UHFFFAOYSA-N
SMILES
CC12CC3CC(C1)(CC(C3)(C2)N)C
MeSH Unique ID
D008559
Source
PubChem CID 4054

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 1,3-Dimethyl-5-aminoadamantane
  • 1-Amino-3,5-dimethyladamantane
  • Memantin
  • Axura
  • D-145
  • D145
  • Ebixa
  • Memantine Hydrochloride
  • Namenda
  • D 145

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(84); was see under AMANTADINE 1984-90; was D 145 see under AMANTADINE 1976-83

MeSH Record

Previous Indexing

  • Amantadine (1974)/analogs & derivatives (1975)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Memantine. Medical Subject Headings (MeSH). 2026. Unique ID D008559. http://id.nlm.nih.gov/mesh/2026/D008559
  2. Memantine. In: Wikipedia. https://en.wikipedia.org/wiki/Memantine
  3. Memantine. In: Wikidata. https://www.wikidata.org/wiki/Q412189
  4. Memantine. In: PubChem Compound. CID 4054. https://pubchem.ncbi.nlm.nih.gov/compound/4054