Structured Summary
Abstract
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H17N
- Molecular Weight
- 151.25 g/mol
- CAS Registry No.
- 768-94-5
- IUPAC Name
- adamantan-1-amine
- InChIKey
- DKNWSYNQZKUICI-UHFFFAOYSA-N
- SMILES
- C1C2CC3CC1CC(C2)(C3)N
- MeSH Unique ID
- D000547
- Source
- PubChem CID 2130
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
52 entry terms
- 1-Aminoadamantane
- Adamantylamine
- 1 Aminoadamantane
- Adekin
- Aman
- Amanta
- Amanta-HCI-AZU
- Amanta-Sulfate-AZU
- Amantadin AL
- Amantadin AZU
- Amantadin Stada
- Amantadin-neuraxpharm
- Amantadin-ratiopharm
- Amantadina Juventus
- Amantadina Llorente
- Amantadine Hydrochloride
- Amantadine Sulfate
- Amixx
- Cerebramed
- Endantadine
- Gen-Amantadine
- Infecto-Flu
- Infex
- Mantadix
- Midantan
- PMS-Amantadine
- Symadine
- Symmetrel
- Viregyt
- Wiregyt
- tregor
- AL, Amantadin
- AZU, Amantadin
- Amanta HCI AZU
- Amanta Sulfate AZU
- AmantaHCIAZU
- AmantaSulfateAZU
- Amantadin neuraxpharm
- Amantadin ratiopharm
- Amantadinneuraxpharm
- Amantadinratiopharm
- Gen Amantadine
- GenAmantadine
- Hydrochloride, Amantadine
- Infecto Flu
- InfectoFlu
- Juventus, Amantadina
- Llorente, Amantadina
- PMS Amantadine
- PMSAmantadine
- Stada, Amantadin
- Sulfate, Amantadine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
68(65)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Amantadine. Medical Subject Headings (MeSH). 2026. Unique ID D000547. http://id.nlm.nih.gov/mesh/2026/D000547
- Amantadine. In: Wikipedia. https://en.wikipedia.org/wiki/Amantadine
- Amantadine. In: Wikidata. https://www.wikidata.org/wiki/Q409761
- Amantadine. In: PubChem Compound. CID 2130. https://pubchem.ncbi.nlm.nih.gov/compound/2130