Chemicals and Drugs

Lim Kinases

Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

6 entry terms
  • LIM Kinase
  • LIM Motif-Containing Protein Kinases
  • LIM-Kinase
  • Kinase, LIM
  • Kinases, Lim
  • LIM Motif Containing Protein Kinases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.542w
  2. D12.776w.476.563w.542w
  3. D12.776w.512.124w

AMA Style

References

  1. National Library of Medicine. Lim Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D054461. http://id.nlm.nih.gov/mesh/2026/D054461
  2. Lim Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/Lim_kinase
  3. Lim Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q17121083