Chemicals and Drugs

LIM Domain Proteins

A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2012

MeSH Hierarchy

Tree Number

  1. D12.776w.512

AMA Style

References

  1. National Library of Medicine. LIM Domain Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D060588. http://id.nlm.nih.gov/mesh/2026/D060588
  2. LIM Domain Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78184721