Structured Summary
Abstract
Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.
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Broader headings
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Synonyms
4 entry terms
- Lewy Body
- Lewy Neurite
- Lewy Neurites
- Neurite, Lewy
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
MeSH Record
Indexing Annotation
LEWY BODY DISEASE is also available
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History Note
92
MeSH Record
Previous Indexing
- Cellular Inclusions (1972-1991)
- Cytoplasmic Granules (1966-1991)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Lewy Bodies. Medical Subject Headings (MeSH). 2026. Unique ID D016631. http://id.nlm.nih.gov/mesh/2026/D016631
- Lewy Bodies. In: Wikipedia. https://en.wikipedia.org/wiki/Lewy_body
- Lewy Bodies. In: Wikidata. https://www.wikidata.org/wiki/Q1822234