Chemicals and Drugs

LDL Lipoproteins

A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.

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Synonyms

21 entry terms
  • Lipoproteins, LDL
  • Low-Density Lipoprotein
  • Low-Density Lipoproteins
  • beta-Lipoprotein
  • beta-Lipoproteins
  • Lipoprotein, Low-Density
  • Lipoproteins, Low-Density
  • Low Density Lipoprotein
  • Low Density Lipoproteins
  • beta Lipoprotein
  • beta Lipoproteins
  • LDL(1)
  • LDL(2)
  • LDL-1
  • LDL-2
  • LDL1
  • LDL2
  • Low-Density Lipoprotein 1
  • Low-Density Lipoprotein 2
  • Low Density Lipoprotein 1
  • Low Density Lipoprotein 2

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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Indexing Annotation

/defic: consider also HYPOBETALIPOPROTEINEMIAS

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History Note

74(72)

MeSH Record

Previous Indexing

  • Lipoproteins (1966-1971)

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References

  1. National Library of Medicine. LDL Lipoproteins. Medical Subject Headings (MeSH). 2026. Unique ID D008077. http://id.nlm.nih.gov/mesh/2026/D008077
  2. LDL Lipoproteins. In: Wikipedia. https://en.wikipedia.org/wiki/Low-density_lipoprotein
  3. LDL Lipoproteins. In: Wikidata. https://www.wikidata.org/wiki/Q28749