Chemicals and Drugs

Human Immunodeficiency Virus Ribonuclease H

A ribonuclease activity that is a component of the HIV REVERSE TRANSCRIPTASE. It removes the RNA strand of the RNA-DNA heteroduplex produced by reverse transcription. Once the RNA moiety is removed a double stranded DNA copy of the HIV RNA can be synthesized.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ribonuclease activity that is a component of the HIV REVERSE TRANSCRIPTASE. It removes the RNA strand of the RNA-DNA heteroduplex produced by reverse transcription. Once the RNA moiety is removed a double stranded DNA copy of the HIV RNA can be synthesized.

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Classification

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Synonyms

5 entry terms
  • RNAse H, HIV
  • Ribonuclease H, HIV
  • Ribonuclease H, Human Immunodeficiency Virus
  • HIV RNAse H
  • HIV Ribonuclease H

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Ribonuclease H (1987-2007)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Human Immunodeficiency Virus Ribonuclease H. Medical Subject Headings (MeSH). 2026. Unique ID D054309. http://id.nlm.nih.gov/mesh/2026/D054309
  2. Human Immunodeficiency Virus Ribonuclease H. In: Wikidata. https://www.wikidata.org/wiki/Q78188465