Structured Summary
Abstract
Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLYPROTEINS) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Sometimes they are synthesized as a gag-pol fusion protein (FUSION PROTEINS, GAG-POL). Pol is short for polymerase, the enzyme class of reverse transcriptase.
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Classification
Related Concepts
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See Also
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Synonyms
9 entry terms
- Gene Product, pol
- Gene Products, pol
- pol Polyprotein
- pol Polyproteins
- pol Protein
- Polyprotein, pol
- Polyproteins, pol
- Protein, pol
- pol Gene Product
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
coord with specific virus (IM)
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History Note
90
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Previous Indexing
- Retroviridae Proteins (1983-1989)
- Reverse Transcriptase (1977-1989)
- Viral Proteins (1977-1989)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. pol Gene Products. Medical Subject Headings (MeSH). 2026. Unique ID D015684. http://id.nlm.nih.gov/mesh/2026/D015684
- pol Gene Products. In: Wikidata. https://www.wikidata.org/wiki/Q77947364