Structured Summary
Abstract
A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS.
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Classification
Broader headings
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Synonyms
9 entry terms
- ALKBH Protein
- AlkB Homolog 1, Histone H2a Dioxygenase
- Alkylated DNA Repair Protein AlkB Homolog 1
- Alpha-Ketoglutarate-Dependent Dioxygenase ABH1
- DNA Lyase ABH1
- DNA Oxidative Demethylase ALKBH1
- ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase
- ABH1, DNA Lyase
- Alpha Ketoglutarate Dependent Dioxygenase ABH1
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- DNA Repair Enzymes (2005-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Histone H2a Dioxygenase AlkB Homolog 1. Medical Subject Headings (MeSH). 2026. Unique ID D000071498. http://id.nlm.nih.gov/mesh/2026/D000071498
- Histone H2a Dioxygenase AlkB Homolog 1. In: Wikidata. https://www.wikidata.org/wiki/Q21481364