Structured Summary
Abstract
A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Heparin Co-Factor II
- Heparin Cofactor 2
- Leuserpin 2
- Protease Inhibitor Leuserpin 2
- Serpin D1
- Heparin Co Factor II
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
90
MeSH Record
Previous Indexing
- Antithrombins (1966-1989)
- Glycoproteins (1966-1989)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Heparin Cofactor II. Medical Subject Headings (MeSH). 2026. Unique ID D015844. http://id.nlm.nih.gov/mesh/2026/D015844
- Heparin Cofactor II. In: Wikidata. https://www.wikidata.org/wiki/Q27185296