Chemicals and Drugs

Antithrombin Proteins

An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

ANTITHROMBINS is also available

MeSH Record

History Note

2011

MeSH Record

Previous Indexing

  • Antithrombins (1976-2010)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.861w.060
  2. D12.776w.872w.060

AMA Style

References

  1. National Library of Medicine. Antithrombin Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D058833. http://id.nlm.nih.gov/mesh/2026/D058833
  2. Antithrombin Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q76876901