Chemicals and Drugs

HIV Protease

Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • HIV Proteinase
  • HTLV-III Protease
  • p16 pol gene product, HIV
  • p16 protease, HIV
  • HIV p16 protease
  • HTLV III Protease
  • Protease, HIV
  • Protease, HTLV-III

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Gene Products, pol (1990)
  • Peptide Peptidohydrolases (1987-1990)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. HIV Protease. Medical Subject Headings (MeSH). 2026. Unique ID D016333. http://id.nlm.nih.gov/mesh/2026/D016333
  2. HIV Protease. In: Wikidata. https://www.wikidata.org/wiki/Q76740132