Chemicals and Drugs

Glucocorticoid Receptors

Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

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Classification

Broader headings

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Synonyms

14 entry terms
  • Glucocorticoid Receptor
  • Glucocorticoids Receptor
  • Receptors, Glucocorticoid
  • Receptors, Glucocorticoids
  • Glucocorticoids Receptors
  • Receptor, Glucocorticoid
  • Receptor, Glucocorticoids
  • Corticoid II Receptor
  • Corticoid Type II Receptor
  • Corticoid Type II Receptors
  • Receptors, Corticoid II
  • Receptors, Corticoid Type II
  • Corticoid II Receptors
  • Receptor, Corticoid II

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

coord IM with specific glucocorticoid (IM)

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History Note

86(77); was see under RECEPTORS, STEROID 1977-85

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Previous Indexing

  • Glucocorticoids (1967-1976)
  • Receptors, Drug (1968-1976)
  • Receptors, Endogenous Substances (1973-1976)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

WK 150

AMA Style

References

  1. National Library of Medicine. Glucocorticoid Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011965. http://id.nlm.nih.gov/mesh/2026/D011965
  2. Glucocorticoid Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q24742015