Chemicals and Drugs

Fentanyl

A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)

Chemical Identity

Chemical Information

Molecular Formula
C22H28N2O
Molecular Weight
336.5 g/mol
CAS Registry No.
437-38-7
IUPAC Name
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
InChIKey
PJMPHNIQZUBGLI-UHFFFAOYSA-N
SMILES
CCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3
MeSH Unique ID
D005283
Source
PubChem CID 3345

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Phentanyl
  • Duragesic
  • Durogesic
  • Fentanest
  • Fentanyl Citrate
  • Fentora
  • R-4263
  • Sublimaze
  • Transmucosal Oral Fentanyl Citrate
  • R 4263
  • R4263

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 89

AMA Style

References

  1. National Library of Medicine. Fentanyl. Medical Subject Headings (MeSH). 2026. Unique ID D005283. http://id.nlm.nih.gov/mesh/2026/D005283
  2. Fentanyl. In: Wikipedia. https://en.wikipedia.org/wiki/Fentanyl
  3. Fentanyl. In: Wikidata. https://www.wikidata.org/wiki/Q407541
  4. Fentanyl. In: PubChem Compound. CID 3345. https://pubchem.ncbi.nlm.nih.gov/compound/3345