Chemicals and Drugs

Alfentanil

A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

Chemical Identity

Chemical Information

Molecular Formula
C21H32N6O3
Molecular Weight
416.5 g/mol
CAS Registry No.
71195-58-9
IUPAC Name
N-[1-[2-(4-ethyl-5-oxotetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide
InChIKey
IDBPHNDTYPBSNI-UHFFFAOYSA-N
SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC
MeSH Unique ID
D015760
Source
PubChem CID 51263

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Alfentanyl
  • Alfenta
  • Alfentanil Hydrochloride
  • Fanaxal
  • Limifen
  • R-39209
  • Rapifen
  • R 39209
  • R39209

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Fentanyl/analogs & derivatives (1966-1989)

MeSH Hierarchy

Tree Number

  1. D03w.383.621.265w.100w

AMA Style

References

  1. National Library of Medicine. Alfentanil. Medical Subject Headings (MeSH). 2026. Unique ID D015760. http://id.nlm.nih.gov/mesh/2026/D015760
  2. Alfentanil. In: Wikipedia. https://en.wikipedia.org/wiki/Alfentanil
  3. Alfentanil. In: Wikidata. https://www.wikidata.org/wiki/Q176533
  4. Alfentanil. In: PubChem Compound. CID 51263. https://pubchem.ncbi.nlm.nih.gov/compound/51263