Chemicals and Drugs

Factor VIII

Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.

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Pharmacological Action

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Synonyms

18 entry terms
  • Blood Coagulation Factor VIII
  • Coagulation Factor VIII
  • Factor 8
  • Factor Eight
  • Thromboplastinogen
  • F VIII-C
  • Factor 8 C
  • Factor VIII Clotting Antigen
  • Factor VIII Coagulant Antigen
  • Factor VIII Procoagulant Activity
  • Factor VIIIC
  • Hyate-C
  • Hyatt-C
  • F VIII C
  • Hyate C
  • HyateC
  • Hyatt C
  • HyattC

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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NLM Classification

WH 310

AMA Style

References

  1. National Library of Medicine. Factor VIII. Medical Subject Headings (MeSH). 2026. Unique ID D005169. http://id.nlm.nih.gov/mesh/2026/D005169
  2. Factor VIII. In: Wikipedia. https://en.wikipedia.org/wiki/Factor_VIII
  3. Factor VIII. In: Wikidata. https://www.wikidata.org/wiki/Q410137