Diseases

Erythropoietic Porphyria

An autosomal recessive porphyria that is due to a deficiency of UROPORPHYRINOGEN III SYNTHASE in the BONE MARROW; also known as congenital erythropoietic porphyria. This disease is characterized by SPLENOMEGALY; ANEMIA; photosensitivity; cutaneous lesions; accumulation of hydroxymethylbilane; and increased excretion of UROPORPHYRINS and COPROPORPHYRINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An autosomal recessive porphyria that is due to a deficiency of UROPORPHYRINOGEN III SYNTHASE in the BONE MARROW; also known as congenital erythropoietic porphyria. This disease is characterized by SPLENOMEGALY; ANEMIA; photosensitivity; cutaneous lesions; accumulation of hydroxymethylbilane; and increased excretion of UROPORPHYRINS and COPROPORPHYRINS.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

16 entry terms
  • Congenital Erythropoietic Porphyria
  • Gunther Disease
  • Gunther's Disease
  • Porphyria, Congenital Erythropoietic
  • Porphyria, Erythropoietic
  • Porphyria, Erythropoietic, Congenital
  • Congenital Erythropoietic Porphyrias
  • Erythropoietic Porphyria, Congenital
  • Erythropoietic Porphyrias
  • Erythropoietic Porphyrias, Congenital
  • Gunthers Disease
  • Porphyrias, Congenital Erythropoietic
  • Porphyrias, Erythropoietic
  • Deficiency of Uroporphyrinogen III Synthase
  • UROS Deficiency
  • Uroporphyrinogen III Synthase, Deficiency of

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

do not confuse with PROTOPORPHYRIA, ERYTHROPOIETIC or PORPHYRIA, HEPATOERYTHROPOIETIC

MeSH Record

History Note

1993

MeSH Record

Previous Indexing

  • Porphyria (1966-1992)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Erythropoietic Porphyria. Medical Subject Headings (MeSH). 2026. Unique ID D017092. http://id.nlm.nih.gov/mesh/2026/D017092
  2. Erythropoietic Porphyria. In: Wikipedia. https://en.wikipedia.org/wiki/Gunther_disease
  3. Erythropoietic Porphyria. In: Wikidata. https://www.wikidata.org/wiki/Q1759389