Anatomy

Epithelioid Cells

Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • Cell, Epithelioid
  • Cells, Epithelioid
  • Epithelioid Cell

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

a type of macrophage; do not confuse with EPITHELIAL CELLS

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Epithelium (1966-1989)
  • Macrophages (1966-1989)

MeSH Hierarchy

Tree Numbers

  1. A11w.329w.372w.300w
  2. A11w.627.482w.300w
  3. A11w.733w.397w.300w
  4. A15.382w.670.522w.300w
  5. A15.382w.680w.397w.300w

AMA Style

References

  1. National Library of Medicine. Epithelioid Cells. Medical Subject Headings (MeSH). 2026. Unique ID D015622. http://id.nlm.nih.gov/mesh/2026/D015622
  2. Epithelioid Cells. In: Wikipedia. https://en.wikipedia.org/wiki/Epithelioid_cell
  3. Epithelioid Cells. In: Wikidata. https://www.wikidata.org/wiki/Q1347440