Chemicals and Drugs

Endothelin-3

A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (N Eng J Med 1995;333(6):356-63)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (N Eng J Med 1995;333(6):356-63)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Endothelin 3
  • Big Endothelin 3
  • Big Endothelin-3
  • Endothelin 3, Big
  • Endothelin-3, Big

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1997; use ENDOTHELINS 1991-1996; for BIG ENDOTHELIN 3 use ENDOTHELIN-3 (NM) 1993-2003

MeSH Record

Previous Indexing

  • Endothelins (1991-1996)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Endothelin-3. Medical Subject Headings (MeSH). 2026. Unique ID D019334. http://id.nlm.nih.gov/mesh/2026/D019334
  2. Endothelin-3. In: Wikidata. https://www.wikidata.org/wiki/Q21112271