Structured Summary
Abstract
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
14 entry terms
- Endothelin Type 1
- Endothelin 1
- Big Endothelin
- Big Endothelin-1
- Endothelin, Big
- Preproendothelin
- Preproendothelin-1
- Proendothelin (1-38)
- Proendothelin-1 Precursor
- Big Endothelin 1
- Endothelin-1, Big
- Precursor, Proendothelin-1
- Preproendothelin 1
- Proendothelin 1 Precursor
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
/drug eff permitted
MeSH Record
History Note
2004(1997); use ENDOTHELINS 1991-96; for BIG ENDOTHELIN use ENDOTHELIN-1 (NM) 1990-2003; for PREPROENDOLTHELIN use ENDOTHELINS-1 (NM) 1989-2003
MeSH Record
Previous Indexing
- Endothelins (1991-1996)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Endothelin-1. Medical Subject Headings (MeSH). 2026. Unique ID D019332. http://id.nlm.nih.gov/mesh/2026/D019332
- Endothelin-1. In: Wikipedia. https://en.wikipedia.org/wiki/Endothelin_1
- Endothelin-1. In: Wikidata. https://www.wikidata.org/wiki/Q390566