Chemicals and Drugs

Edaravone

An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.

Chemical Identity

Chemical Information

Molecular Formula
C10H10N2O
Molecular Weight
174.20 g/mol
CAS Registry No.
89-25-8
IUPAC Name
5-methyl-2-phenyl-4H-pyrazol-3-one
InChIKey
QELUYTUMUWHWMC-UHFFFAOYSA-N
SMILES
CC1=NN(C(=O)C1)C2=CC=CC=C2
MeSH Unique ID
D000077553
Source
PubChem CID 4021

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Edarabone
  • Norantipyrine
  • Norphenazone
  • 1-Phenyl-3-methyl-5-pyrazolone
  • 3-Methyl-1-phenyl-2-pyrazolin-5-one
  • MCI 186
  • MCI-186
  • Phenylmethylpyrazolone
  • Radicava
  • 1 Phenyl 3 methyl 5 pyrazolone
  • 3 Methyl 1 phenyl 2 pyrazolin 5 one
  • MCI186

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1970)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Edaravone. Medical Subject Headings (MeSH). 2026. Unique ID D000077553. http://id.nlm.nih.gov/mesh/2026/D000077553
  2. Edaravone. In: Wikipedia. https://en.wikipedia.org/wiki/Edaravone
  3. Edaravone. In: Wikidata. https://www.wikidata.org/wiki/Q335099
  4. Edaravone. In: PubChem Compound. CID 4021. https://pubchem.ncbi.nlm.nih.gov/compound/4021