Chemicals and Drugs

Antipyrine

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Chemical Identity

Chemical Information

Molecular Formula
C11H12N2O
Molecular Weight
188.23 g/mol
CAS Registry No.
60-80-0
IUPAC Name
1,5-dimethyl-2-phenylpyrazol-3-one
InChIKey
VEQOALNAAJBPNY-UHFFFAOYSA-N
SMILES
CC1=CC(=O)N(N1C)C2=CC=CC=C2
MeSH Unique ID
D000983
Source
PubChem CID 2206

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Phenazone
  • Anodynin
  • Pyramidone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Antipyrine. Medical Subject Headings (MeSH). 2026. Unique ID D000983. http://id.nlm.nih.gov/mesh/2026/D000983
  2. Antipyrine. In: Wikipedia. https://en.wikipedia.org/wiki/Phenazone
  3. Antipyrine. In: Wikidata. https://www.wikidata.org/wiki/Q415578
  4. Antipyrine. In: PubChem Compound. CID 2206. https://pubchem.ncbi.nlm.nih.gov/compound/2206