Chemicals and Drugs

Duloxetine Hydrochloride

A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Duloxetine HCl
  • HCl, Duloxetine
  • Hydrochloride, Duloxetine
  • Cymbalta
  • Duloxetine
  • Duloxetine Ethanedioate (1:1), (+-)-isomer - T353987
  • Duloxetine, (+)-isomer
  • LY 227942
  • LY 248686
  • LY-227942
  • LY-248686
  • LY227942
  • N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine
  • N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide
  • LY248686

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1989)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Duloxetine Hydrochloride. Medical Subject Headings (MeSH). 2026. Unique ID D000068736. http://id.nlm.nih.gov/mesh/2026/D000068736
  2. Duloxetine Hydrochloride. In: Wikidata. https://www.wikidata.org/wiki/Q27116971