Structured Summary
Abstract
Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS.
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Synonyms
3 entry terms
- Diterpene Alkaloid
- Alkaloid, Diterpene
- Alkaloids, Diterpene
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Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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History Note
2019
MeSH Record
Previous Indexing
- Alkaloids (1963-2018)
- Diterpenes (1963-2018)
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References
- National Library of Medicine. Diterpene Alkaloids. Medical Subject Headings (MeSH). 2026. Unique ID D000077743. http://id.nlm.nih.gov/mesh/2026/D000077743
- Diterpene Alkaloids. In: Wikipedia. https://en.wikipedia.org/wiki/Diterpene_alkaloids
- Diterpene Alkaloids. In: Wikidata. https://www.wikidata.org/wiki/Q94962804