Structured Summary
Abstract
A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
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Classification
Broader headings
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Synonyms
17 entry terms
- CD52 Protein
- CDw52 Antigen
- Cambridge Pathology 1 Antigen
- Campath-1 Antigen
- Campath-1 Receptor
- Campath-1H Antigen
- HLA-Bw52
- HLA-Bw52 Antigen
- Lymphocyte Antigen CD52
- Lymphocyte Antigen CDw52
- CD52, Lymphocyte Antigen
- CDw52, Lymphocyte Antigen
- Campath 1 Antigen
- Campath 1 Receptor
- Campath 1H Antigen
- HLA Bw52
- HLA Bw52 Antigen
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Antigens, CD (1991-2017)
- Antigens, Neoplasm (1991-2017)
- Glycoproteins (1991-2017)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. CD52 Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D000074301. http://id.nlm.nih.gov/mesh/2026/D000074301
- CD52 Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q24784808